San Carlos National Museum (Museo Nacional de San Carlos) is about 3 blks. n. of Plaza de la República at Puente de Alvarado #50 (M: Revolución, line 2). It houses an impressive collection of paintings by European artists spanning the 15th through the 19th centuries, including works by Francisco José de Goya, Tintoretto, Titian, Anthony Van Dyck, Rembrandt and Peter Paul Rubens.
The lovely neoclassic building has a rotunda-like design and was once a private home for such notable Mexican military figures as Gen. Agustín de Iturbide and Gen. Antonio López de Santa Anna. There's a small public park behind the rear of the museum, off Puente de Alvarado.