42.3 miles: 0 hours, 55 minutes
Missouri’s SR 19 is a favorite for Sunday drivers and motorcyclists, because of its roller coaster hills and curving path. It’s most vibrant in the spring, as the flowering trees are blooming. When you need a rest, stop at some of the roadside and river parks and enjoy the colorful wildflowers. The area between Winona and Salem is also full of natural springs—at least 60 of them bubble up from the old volcanic rock.