Mark Twain Boyhood Home and Museum is at 206 Hill St. The complex consists of eight historic buildings and museums related to Hannibal's most famous resident. The home where Samuel Clemens lived between the ages of 7 and 18 was built by his father, John Marshall Clemens, in 1843. The restored two-story frame house is decorated with period furnishings, and the museum properties contain interpretive displays, including photographs, first editions of Twain's books, original manuscripts and the desk where he wrote “The Adventures of Tom Sawyer.” A 10-minute video presentation about his life is shown in the annex behind the home and museum.
The Becky Thatcher House is the home of Laura Hawkins, a childhood friend of Twain's who was the inspiration for his Thatcher character. The Huckleberry Finn House is a reconstruction of Tom Blankenship's house, Twain's inspiration for Huck Finn. Pilaster House (closed for renovations), an old drugstore, was the home of Dr. Orville Grant, a close Clemens family friend. The family moved into Dr. Grant's house after losing their own home. There also is an interpretive center with a Clemens family timeline, and you can visit the John M. Clemens Justice of the Peace Office on Hill Street (originally located on Bird Street).
The Mark Twain Museum, 2 blocks south on Main Street, features 15 original Norman Rockwell oil paintings that were used as illustrations in special editions of “The Adventures of Tom Sawyer” and “The Adventures of Huckleberry Finn”; sketches for the paintings were done by Rockwell in Hannibal 1935-36. Interactive displays depict scenes from Twain's life and writings, and live performances take place April through September.