Skip to main content
Header image

Route 66 - Eastern Missouri

88.3 miles: 3 hours, 5 minutes

“The Mother Road” wraps up its trek across the breadth of The Show Me State as it heads toward the Illinois border. There are several Route 66 icons in and around St. Louis, including Ted Drewes, a frozen custard stand that's been in business since 1929. A concrete (think extra thick milkshake) at Ted's is a St. Louis summertime tradition.


St. Clair, MO to St. Louis, MO

61.5 miles: 1 hours, 53 minutes

Courtesy of Missouri Botanical Garden

After leaving St. Clair, you won't spend much time on I-44 before reaching the outer St. Louis suburbs. En route on old Route 66 is the site of Times Beach, founded in the 1920s as a Meramec River resort. A toxic waste contamination in the early 1980s rendered the town uninhabitable; the pollution was cleaned up and today the area is Route 66 State Park.


St. Louis, MO to Edwardsville, IL

26.8 miles: 1 hours, 11 minutes

Getty Images/Jeremy Woodhouse

Following old Route 66 through St. Louis can be maddening, since several streets have a “66” connection. Historic Chain of Rocks Bridge—now a mile-long hiking and biking trail just south of I-270—was the former Mississippi River crossing point. Don’t leave St. Louis without visiting The Arch, symbolic “gateway to the West.”


Travel Like an Expert with AAA and Trip Canvas

Get Ideas from the Pros

As one of the largest travel agencies in North America, we have a wealth of recommendations to share! Browse our articles and videos for inspiration, or dive right in with preplanned AAA Road Trips, cruises and vacation tours.

Build and Research Your Options

Save and organize every aspect of your trip including cruises, hotels, activities, transportation and more. Book hotels confidently using our AAA Diamond Designations and verified reviews.

Book Everything in One Place

From cruises to day tours, buy all parts of your vacation in one transaction, or work with our nationwide network of AAA Travel Agents to secure the trip of your dreams!