Texas' oldest town, Nacogdoches (Nak-a-DOE-chez) was named for the region's earliest inhabitants, a Caddo Indian tribe. Hernando de Soto's lieutenant probably visited the area en route to Mexico 1541-42, after de Soto's death. The expedition of René-Robert Cavelier, Sieur de La Salle, documented the settlement in 1687. Learn More...